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QDR3 / YBR043C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
AQR2 22
Feature Type
ORF , Verified
Description
Multidrug transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; has a role in polyamine homeostasis; involved in spore wall asembly; sequence similarity to DTR1 and QDR1, and the triple mutant dtr1 qdr1 qdr3 exhibits reduced dityrosine fluorescence relative to the single mutants; expression is upregulated under polyamine stress; required for resistance to quinidine, barban, cisplatin, and bleomycin 1 2 3 4 5

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