GAL10 / YBR019C Homology


Standard Name
GAL10 1
Systematic Name
YBR019C
SGD ID
SGD:S000000223
Feature Type
ORF , Verified
Description
UDP-glucose-4-epimerase; catalyzes interconversion of UDP-galactose and UDP-D-glucose in galactose metabolism; also catalyzes conversion of alpha-D-glucose or alpha-D-galactose to their beta-anomers; human homolog GALE implicated in galactosemia, can complement yeast null mutant 2 3
Name Description
GALactose metabolism
Comparative Info

Homologs

Homology calls are sourced from the Alliance of Genome Resources. Many aspects of data integration presented at the Alliance require a common set of orthology relationships among genes for the organisms represented, including human. The Alliance provides the results of all methods that have been benchmarked by the Quest for Orthologs Consortium (QfO). The homolog inferences from the different methods have been integrated using the DRSC Integrative Ortholog Prediction Tool (DIOPT), which integrates a number of existing methods including those used by the Alliance: Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, and ZFIN.


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Species Gene ID Gene name Source

Functional Complementation

Information about cross-species functional complementation between yeast and other species, curated by SGD and the Princeton Protein Orthology Database (P-POD).

3 entries for 3 complements


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SpeciesGene IDStrain backgroundDirectionDetailsSourceReference
Homo sapiensHGNC:4116S288Cother complements yeastWild-type human GALE complements yeast mutation but a disease-associated allele does notSGDMcCorvie TJ, et al. (2012)
PMID:22613355
Homo sapiensHGNC:4116W303other complements yeastGALE p.R51W rescues gal10-Δ; mutation associated with thrombocytopeniaSGDSeo A, et al. (2019)
PMID:30247636
Homo sapiensHGNC:4116S288Cother complements yeastSGDChhay JS, et al. (2008)
PMID:18188677
Showing 1 to 3 of 3 entries

Fungal Homologs

Fungal Homology calls are sourced from AllianceMine, which compiles fungal homology calls from FungiDB, CGD, Panther, PomBase, TreeFam, HomoloGene, and SGD.


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Species Gene ID Gene name Description Source

External Identifiers

List of external identifiers for the protein from various database sources.

33 entries for 11 sources


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External IDSource
orf19.3672CGD
4891DIP
5.1.3.2ExPASy
5.1.3.3ExPASy
CAA84961.1GenBank/EMBL/DDBJ
CAA57106.1GenBank/EMBL/DDBJ
AAA34630.1GenBank/EMBL/DDBJ
6319493GenBank/EMBL/DDBJ
K02115GenBank/EMBL/DDBJ
Z35888GenBank/EMBL/DDBJ
Showing 1 to 10 of 33 entries

Resources