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PRS4 / YBL068W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Protein Product
ribose phosphate diphosphokinase subunit PRS4
Feature Type
ORF , Verified
Description
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP; which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes; PRS4 has a paralog, PRS2, that arose from the whole genome duplication; a missense mutation in the conserved residue R196 of its human homolog PRPS1 is pathogenic 1 2 3 5 6
Paralog
PRS2 5
EC Number
2.7.6.1

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