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ALK2 / YBL009W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Protein Product
protein kinase ALK2
Feature Type
ORF , Verified
Description
Atypical protein kinase; along with its paralog, ALK1, required for proper spindle positioning and nuclear segregation following mitotic arrest, proper organization of cell polarity factors in mitosis, proper localization of formins and polarity factors, and survival in cells that activate spindle assembly checkpoint; negatively regulates the morphogenesis checkpoint in response to polarity insults in opposition to ALK1; phosphorylated in response to DNA damage; similar to mammalian haspins 1 2 3
Paralog
ALK1
EC Number
2.7.11.1

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