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CDC15 / YAR019C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

LYT1 10 , RLT1 11
Protein Product
serine/threonine protein kinase CDC15
Feature Type
ORF , Verified
Hippo-like kinase of the Mitotic Exit Network; promotes exit by activating the Dbf2p kinase; component of a non-canonical Hippo pathway with Sps1p required for prospore membrane closure, spindle disassembly and sustained release of Cdc14p during meiotic anaphase II; complexes with Sps1p and contributes to its phosphorylation; phosphorylates the RNAPII CTD during mitosis; localizes to the bud neck and SPB during anaphase and telophase; relocalizes to the cytoplasm upon DNA replication stress 3 5 6 7 8 9
EC Number