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RFA1 / YAR007C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

BUF2 21 , FUN3 22 , RPA1 23 , RPA70 24
Protein Product
replication factor A subunit protein RFA1
Feature Type
ORF , Verified
Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; role in DNA catenation/decatenation pathway of chromosome disentangling; relocalizes to the cytosol in response to hypoxia 1 2 3 4 5 6