Sequence Help

CLN3 / YAL040C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

DAF1 12 , FUN10 13 , WHI1 2
Protein Product
cyclin CLN3
Feature Type
ORF , Verified
G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote G1 to S phase transition; plays a role in regulating transcription of other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis; acetyl-CoA induces CLN3 transcription in response to nutrient repletion to promote cell-cycle entry; cell cycle arrest phenotype of the cln1 cln2 cln3 triple null mutant is complemented by any of human cyclins CCNA2, CCNB1, CCNC, CCND1, or CCNE1 2 3 4 5 6