Sequence Help
DRS2 / YAL026C Sequence
Sequences and genome annotation information for Reference Strain S288C and a select set of
Alternative References.
- Aliases
-
SWA3
,
FUN38
14
- Protein Product
-
aminophospholipid-translocating P4-type ATPase DRS2
- Feature Type
- ORF
, Verified
- Description
-
Trans-golgi network aminophospholipid translocase (flippase); maintains membrane lipid asymmetry in post-Golgi secretory vesicles; contributes to clathrin-coated vesicle formation, endocytosis, protein trafficking between the Golgi and endosomal system and the cellular response to mating pheromone; autoinhibited by its C-terminal tail; localizes to the trans-Golgi network; mutations in human homolog ATP8B1 result in liver disease
2
3
4
5
6
7
8
9
- EC Number
-
7.6.2.1