Sequence Help

DRS2 / YAL026C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

SWA3 , FUN38 14
Protein Product
aminophospholipid-translocating P4-type ATPase DRS2
Feature Type
ORF , Verified
Trans-golgi network aminophospholipid translocase (flippase); maintains membrane lipid asymmetry in post-Golgi secretory vesicles; contributes to clathrin-coated vesicle formation, endocytosis, protein trafficking between the Golgi and endosomal system and the cellular response to mating pheromone; autoinhibited by its C-terminal tail; localizes to the trans-Golgi network; mutations in human homolog ATP8B1 result in liver disease 2 3 4 5 6 7 8 9
EC Number