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SED5-SLY1 SNARE chaperone complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Summary
SNARE regulatory complex which controls vesicle-mediated membrane trafficking between the endoplasmic reticulum (ER) and Golgi apparatus in yeast. SLY1 binds directly to the N-terminal region of SED5, an essential syntaxin, stabilizing it and facilitating the assembly of SNARE complexes that drive membrane fusion. The SLY1 N-lobe is anchored to SED5 on the target organelle while the SlLY1 regulatory loop binds the incoming vesicle’s lipid bilayer This interaction enhances the specificity and efficiency of vesicle docking and fusion, thereby ensuring proper intracellular transport and maintaining cellular organization.

Biological Process

Manually curated GO annotations reflect our best understanding of the basic biological process for this protein complex. Manually curated annotations are assigned by curators based on published papers when available, or by curatorial statements if necessary. Curators periodically review all manually curated GO annotations for accuracy and completeness.

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Qualifier Gene Ontology Term Annotation Extension Evidence Source Assigned On Reference

Molecular Function

Manually curated GO annotations reflect our best understanding of the basic molecular function for this protein complex. Manually curated annotations are assigned by curators based on published papers when available, or by curatorial statements if necessary. Curators periodically review all manually curated GO annotations for accuracy and completeness.

Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

Qualifier Gene Ontology Term Annotation Extension Evidence Source Assigned On Reference

Shared Annotations

This diagram displays Gene Ontology terms (green) that are shared between the given macromolecular complex (black) and other yeast complexes (yellow). Note: No diagram is shown ("No shared annotations") if there are less than 2 shared GO annotations between this complex and any other complexes.

No shared annotations