Gene Ontology Help

Kinetochore CCAN complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Interacts with duplex DNA and facilitates accurate chromosome segregation. Plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. It may be involved in incorporation of newly synthesized CENPA (P36012) into centromeres to form CENP-A nucleosomes (CPX-5705). Required for chromosome congression and efficient alignment of the chromosomes on a metaphase plate.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

DNA binding, chromosome segregation, nucleus, organelle