Gene Ontology Help

RQT ribosome-associated quality control trigger complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Recognizes ubiquitinated stalled ribosomes and induces subunit dissociation to facilitate the ribosome-associated quality control (RQC) pathway. The complex associates with E3 ubiquitin-ligase HEL2 (Q05580)-ribosome complexes and required for the primary steps of RQC. The ubiquitin-binding activity of RQT3 and ATPase activity of CUE3 were crucial to trigger the RQC complex (CPX-3265).
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

helicase activity, ion binding, catabolic process, proteolysis involved in protein catabolic process