Gene Ontology Help

Endosomal SNARE complex TLG2-VTI1-TLG1-SNC2 Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

SNARE complex required for the fusion of endosomal vesicles with the trans-Golgi network. Mediates membrane fusion through the spontaneous assembly of four complementary SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) motifs. SNAREs bind to each other in-trans, that is, with SNAREs anchored in each apposed tethered membrane. The assembly process leads to a tight connection between the fusing membranes and initiates membrane fusion.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

endocytosis, endosomal transport, membrane fusion, membrane organization, organelle fusion, transport, vesicle organization, vesicle-mediated transport, SNARE complex