Gene Ontology Help

HMC complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Represses HAP1 activity in the absence of heme, thus modulating oxygen dependent gene expression. The HMC complex is associated with low DNA-binding and transcriptional activities. Heme disrupts the HMC and allows HAP1 to form a dimer, with higher DNA-binding and transcription rate properties.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

biological process