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GPI-anchor transamidase complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Transamidase enzyme complex that transfers the glycosylphosphatidylinositol (GPI) lipid to the newly made GPI protein in the endoplasmic reticulum, replacing the C-terminal GPI attachment signal peptide of a protein with the lipid. GPI is a complex glycolipid with a core structure, phosphoethanolamine-6-mannose-alpha1,2-mannose-alpha1,6-mannose-alpha1,4-glucosamine-alpha1,6-inositol-phospholipid that functions as a membrane anchor for many cell surface proteins.