Gene Ontology Help

RAP1-GCR1-GCR2 transcription activation complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Transcription factor required for the transcription of glycolytic genes. Appears to simultaneously bind to two adjacent DNA elements (UAS(RPG) and the CT box, bound specifically by RAP1 and GCR1, respectively). The complex can activate transcription through isolated UAS(RPG) ((upstream activating sequence in ribosomal protein genes)) but not CT elements. CT box-dependent transcriptional activation requires GCR2. GCR2 is essential only for the expression of CT box-containing glycolytic genes, but not for ribosomal genes, which do not have a CT box. GCR2 tappears to induce a conformation change in GCR1 and/or stimulate its hyperphosphorylation.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

DNA binding, biological process, nucleus, organelle