RAD6-UBR2 ubiquitin ligase complex

RAD6-UBR2 ubiquitin ligase complex Literature

Unique References: 8
Aliases: RAD6-UBR2 complex , RAD6/UBC2-UBR2 complex , RAD6/UBC2-UBR2 ubiquitin ligase complex , UBC2-UBR2 complex , UBC2-UBR2 ubiquitin ligase complex

Primary Literature

Nillegoda NB, et al. (2010) Ubr1 and Ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins. Mol Biol Cell 21(13):2102-16 PMID: 20462952
Wang L, et al. (2004) Rpn4 is a physiological substrate of the Ubr2 ubiquitin ligase. J Biol Chem 279(53):55218-23 PMID: 15504724
Jentsch S, et al. (1987) The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme. Nature 329(6135):131-4 PMID: 3306404

Additional Literature

Sahoo A and Pechmann S (2022) Functional network motifs defined through integration of protein-protein and genetic interactions. PeerJ 10:e13016 PMID: 35223214

Wood A, et al. (2003) Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter. Mol Cell 11(1):267-74 PMID: 12535539

Bailly V, et al. (1997) Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities. J Biol Chem 272(37):23360-5 PMID: 9287349

Watkins JF, et al. (1993) The extremely conserved amino terminus of RAD6 ubiquitin-conjugating enzyme is essential for amino-end rule-dependent protein degradation. Genes Dev 7(2):250-61 PMID: 8436296

Dohmen RJ, et al. (1991) The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme. Proc Natl Acad Sci U S A 88(16):7351-5 PMID: 1651502

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RAD6-UBR2 ubiquitin ligase complex Literature

Primary Literature

Additional Literature