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Superoxide dismutase 1 copper chaperone Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Copper chaperone for superoxide dismutase which delivers copper to the [Cu-Zn] superoxide dismutase I (SOD1, CPX-2896) forming heterodimer (CPX-2267). Insertion of copper is required for SOD1 enzymatic activity. Oxidation of an intramolecular disulfide bond is required to increase the enzymatic activity from approximately 10 % in disulfide-reduced SOD1 to 100 % in disulfide-oxidized SOD1. The copper chaperone, CCS1, both delivers the copper and oxidises the disulfide bond.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

molecular function, monoatomic ion transport, protein maturation, transport