Gene Ontology Help

Mitochondrial respiratory chain complex IV, COX5A variant Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Key role in aerobic respiration, in which mitochondrial enzymes accept electrons from electron carriers reduced in glycolysis and the tricarboxylic acid cycle. A complex metalloprotein that transfers electrons from reduced cytochrome c to molecular oxygen and conserves the free energy released in this exergonic reaction by maintaining a transmembrane proton gradient which is utilized to drive the synthesis of ATP or ion transport across the membrane. The four protons consumed in the reduction of one oxygen molecule to water are taken from the mitochondrial matrix and, coupled to this reaction, four additional protons are translocated from the matrix to the intermembrane space.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

oxidoreductase activity, transmembrane transporter activity, cellular respiration, generation of precursor metabolites and energy, membrane