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Gene Ontology Help

EMP24 complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Summary
Plays a role in selective transport processes at the ER-Golgi interface by tethering both COPI (CPX-1652) and COPII (CPX-2523) complexes via dilysine motives on EMP24 and ERV25. May initially recruit the deactivated form of ARF1 (P11076), facilitating the formation of a COPI priming complex and subsequently enabling efficient budding. In addition, the ability of p24 proteins to oligomerize and to present multiple coatomer-binding motifs may promote COPI budding by docking coatomer more firmly to the membrane. Required for the export of glycosylphosphatidylinositol-anchored proteins to the Golgi apparatus through interaction with the SEC23-LST1 COPII cargo recruitment complex (CPX-1341).
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

Golgi vesicle transport, membrane organization, transport, vesicle organization, vesicle-mediated transport, cytoplasmic vesicle, membrane, organelle

Biological Process

Manually curated GO annotations reflect our best understanding of the basic biological process for this protein complex. Manually curated annotations are assigned by curators based on published papers when available, or by curatorial statements if necessary. Curators periodically review all manually curated GO annotations for accuracy and completeness.

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Qualifier Gene Ontology Term Annotation Extension Evidence Source Assigned On Reference

Cellular Component

Manually curated GO annotations reflect our best understanding of the basic cellular component for this protein complex. Manually curated annotations are assigned by curators based on published papers when available, or by curatorial statements if necessary. Curators periodically review all manually curated GO annotations for accuracy and completeness.

Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

Qualifier Gene Ontology Term Annotation Extension Evidence Source Assigned On Reference

Shared Annotations

This diagram displays Gene Ontology terms (green) that are shared between the given macromolecular complex (black) and other yeast complexes (yellow). Note: No diagram is shown ("No shared annotations") if there are less than 2 shared GO annotations between this complex and any other complexes.