Gene Ontology Help

DNA-directed RNA Polymerase I complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Catalyzes the transcription of ribosomal RNA from a DNA template by acting as a nucleotidyl transferase that polymerizes ribonucleotides at the 3' end of an RNA transcript synthesizing precursors of rRNAs. Forms inactive dimers whereas initiation-competent Pol I is monomeric. Initiation of transcription requires the assembly of the upstream activating factor (UAF, CPX-1101), the core factor (CPX-1836), the TATA binding protein SPT15, and RNAP-I with RRN3 on the upstream element and core promoter. Upon transcription initiation, UAF, RRN3 and CF dissociate from the promoter.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

DNA binding, RNA binding, nucleotidyltransferase activity, rRNA binding, transferase activity, DNA-templated transcription, DNA-templated transcription elongation, DNA-templated transcription initiation, DNA-templated transcription termination, biosynthetic process, transcription by RNA polymerase I, nucleus, organelle