Gene Ontology Help

COPI vesicle coat complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Coats vesicles which bud from the Golgi membrane and subsequently transport proteins from the cis end of the Golgi complex back to the rough endoplasmic reticulum (ER), where they were originally synthesized (retrograde transport), and between Golgi compartments. The complex binds to di-lysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi to the trans Golgi network. Cargo containing the sorting motifs KKXX and KXKXX interact with COPI to form carriers.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

structural molecule activity, Golgi vesicle transport, transport, vesicle-mediated transport