Gene Ontology Help

Elongator holoenzyme complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
N-acetyltransferase which acts to form modified wobble uridines in tRNA, such as 5-methoxycarbonylmethyl-uridine (mcm5U), 5-methoxycarbonylmethyl-2-thio-uridine (mcm5s2U), and 5-carbamoylmethyl-uridine (ncm5U). These sites influence the recognition rate and affinity between incoming tRNAs and codons in the A site of the translating ribosome, stablizing transient pausing events thus supporting proper domain folding of the nascent polypeptide chains during the elongation phase of the ribosome?mediated translation process.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

RNA binding, acyltransferase activity, transferase activity, RNA modification, cellular nitrogen compound metabolic process, regulation of translation, tRNA metabolic process, tRNA processing, elongator holoenzyme complex