Gene Ontology Help

SAS acetyltransferase complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Histone acetyltransferase (HAT) complex capable of acetylating both free histones and nucleosomes, although the nucleosomal HAT activity of SAS complex is relatively weak. Exclusively acetylates Lys-16 of histone H4 and may provide a barrier to Sir (silent information regulator) proteins that would prevent adjacent euchromatic regions from being transcriptionally inactivated. The complex appears to assemble in the nucleus, following the separate import of the components.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

acyltransferase activity, transferase activity, chromatin organization, histone modification, peptidyl-amino acid modification, protein acylation, NuA4 histone acetyltransferase complex, Piccolo NuA4 histone acetyltransferase complex, SAS acetyltransferase complex, histone acetyltransferase complex