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Mitochondrial degradosome complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Plays an essential role in mitochondrial RNA turnover, degrading structured RNA in an ATP-dependent manner. Helicase activity of the degradosome is more efficient with substrates with 3'-overhangs, and requires the presence of DSS1. Unprocessed rRNA and mRNA accumulate in cells lacking degradosome activity, however, tRNA maturation is unaffected, indicating that this complex is not directly involved in RNA processing. Instead, the degradosome complex is likely part of the mitochondrial RNA surveillance system, which degrades aberrant and unprocessed RNAs.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

RNA binding, helicase activity, hydrolase activity, nuclease activity, RNA catabolic process, catabolic process, nucleobase-containing compound catabolic process