Gene Ontology Help

LSM1-7 complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Lsm1-7 is a complex conserved in all eukaryotes and has similar function to the homohexamer Hfq in bacteria. It is an important part of cytoplasmic mRNA degradation. It preferentially binds oligo-adenylated (but not poly-A) mRNAs at their 3' end and promotes decapping at the 5' end thereby directing the mRNA for degradation through the 5' to 3' pathway. Lsm1-7 in yeast can be isolated as part of the Lsm1-7-Pat1 complex.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

RNA binding, mRNA binding, RNA catabolic process, catabolic process, nucleobase-containing compound catabolic process, organelle, P-body, intracellular non-membrane-bounded organelle