Gene Ontology Help

LSM2-8 complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
The hetero-heptameric complex of seven Lsm proteins (Lsm2-8) affects the processing of small stable RNAs (including tRNAs, rRNAs) and pre-mRNAs in the nucleus. The complex is part of the U6 snRNA, where it binds to the U6 RNA and contributes to stabilizing the U6 snRNA and chaperoning it through the splicing process. The Lsm2-8 complex is thought to pre-exist in the cell and bind to U6 as a complex.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

RNA binding, RNA splicing, cellular nitrogen compound metabolic process, mRNA processing, rRNA processing, tRNA metabolic process, tRNA processing, nucleus, organelle