Gene Ontology Help

Sm complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Essential role in pre-mRNA splicing. Form a heteroheptameric complex on binding to a conserved Sm site [consensus AU(4-6)G] found in single-stranded regions of U1, U2, U4 and U5 snRNAs. U1, U2, U4 and U5 snRNAs are produced in the nucleus by RNA polymerase II and exported to the cytoplasm, where the Sm proteins bind to them and promote the hypermethylation of the N7-monomethyl guanosine cap at their 5-prime-ends, to produce the 2,2,7-trimethyl guanosine cap structure.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

RNA binding, RNA modification, RNA splicing, mRNA processing