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U2 small nuclear ribonucleoprotein complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Non-coding RNA containing complex that is involved in mRNA splicing. U2 snRNP binds to the intron branch site of the commitment complex (CPX-1418) to form the pre-spliceosome in an ATP dependent step. The spliceosome is a highly dynamic structure, assembled by sequential binding and release of the small nuclear RNAs and protein factors which removes intronic sequence from pre-mRNA. During formation of the activated spliceosome, U2 will replace the dissociating U4 (CPX-31) to form base pairs with U6 (CPX-24). Prior to the first catalytic reaction, the SF3a (CPX-1648) and SF3b (CPX-1647) sub-complexes dissociate from the spliceosome, presumably making the branch site accessible to lariat formation.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

RNA binding, RNA splicing, cellular component assembly, cellular nitrogen compound metabolic process, mRNA processing, protein-containing complex assembly, ribonucleoprotein complex assembly, nucleus, organelle, U2 snRNP, ribonucleoprotein complex, small nuclear ribonucleoprotein complex, spliceosomal complex