Gene Ontology Help

Exocyst Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Recruited to sites of active exocytosis and membrane expansion, where it mediates the tethering of secretory vesicles to the plasma membrane in preparation for soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein receptor (SNARE)-mediated membrane fusion. The exocyst is localized to the emerging bud tip, where it mediates exocytosis for the asymmetric expansion of daughter cell surfaces during polarized cell growth. During cytokinesis, the exocyst is localized to the mother–daughter cell junction to mediate abscission. The targeting of secretory vesicles to the plasma membrane involves direct interactions of the exocyst with PI(4,5)P2. In addition, a number of small GTP-binding proteins interact with components of the exocyst and regulate the assembly, localization, and function of this complex.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

ion binding, lipid binding, biological process