Gene Ontology Help

GET4-GET5 transmembrane domain recognition complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Escorts newly-synthesised tail-anchored proteins to GET3 (Q12154) for insertion into the endoplasmic reticulum membrane through the GET complex (CPX-956). The complex acts both as an active tethering device that brings GET3 into proximity with its substrates and enzymatically activates GET3 for transmembrane domain recognition. The complex may contain additional heat-shock domain proteins, and it is unclear how many of these are bound at any one time.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

molecular function, protein targeting, transport, cytosol, TRC complex