Gene Ontology Help

Myosin class II complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Building block of the class II myosin bipolar filament, responsible for the anti-parallel sliding of actin filaments. Plays a role in cell separation, appearing to form thick filaments that scaffold the assembly of the division machinery. The myosin heavy chain motor domain mediates the ATP-dependent interaction with the F-actin cytoskeleton. The myosin neck region with the bound light chains acts as a rigid lever arm that amplifies movements within the myosin motor domain into a large mechanical stroke that directionally propels the myosin along the actin filament.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

ATP hydrolysis activity, cytoskeletal protein binding, hydrolase activity, ion binding, biological process, site of polarized growth, myosin II complex