Gene Ontology Help

SNX4-SNX41 sorting nexin complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Required on a maturing endosome to sort and export distinct cargo proteins. The heterodimers oligomerize and coat the membrane, driving a transition in topology from a flat membrane to a form the tubular endosomal network thus generating transport vesicles for trafficking of retromer cargoes . SNX4-SNX41 mediates retrograde sorting of ATG27(P46989), an integral membrane protein implicated in selective autophagy.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

catabolic process, endosomal transport, transport, vesicle-mediated transport, cellular component