Gene Ontology Help

RCL1-BMS1 40S ribosomal subunit maturation complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Required for 40S ribosomal subunit maturation. Formation of the complex is required for the import of RCL1 into the nucleus. In the absence of GTP, BMS1 acts as a chaperone and masks the RCL1 active site. GTP binding to BMS1 and/or GTP hydrolysis unveils the RNA binding surface of RCL1 and promotes 20S pre-rRNA cleavage to form the mature 18S RNA.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

GTPase activity, RNA binding, hydrolase activity, rRNA binding, ribosomal small subunit biogenesis, nucleolus, organelle, intracellular non-membrane-bounded organelle