Primary Literature
TEXT HERE
- Jiang YK, et al. (2023) Two independent DNA repair pathways cause mutagenesis in template switching deficient Saccharomyces cerevisiae. Genetics 225(3) PMID: 37594077
- McPherson KS, et al. (2023) Evolution of Rev7 interactions in eukaryotic TLS DNA polymerase Polζ. J Biol Chem 299(2):102859 PMID: 36592930
- Malik R, et al. (2022) Cryo-EM structure of translesion DNA synthesis polymerase ζ with a base pair mismatch. Nat Commun 13(1):1050 PMID: 35217661
- Siebler HM, et al. (2022) DNA Polymerase ζ without the C-Terminus of Catalytic Subunit Rev3 Retains Characteristic Activity, but Alters Mutation Specificity of Ultraviolet Radiation in Yeast. Genes (Basel) 13(9) PMID: 36140745
- Halas A, et al. (2021) Developmental delay with hypotrophy associated with homozygous functionally relevant REV3L variant. J Mol Med (Berl) 99(3):415-423 PMID: 33474647
- Jiang G, et al. (2021) Molecular Mechanism of the Cytosine CRISPR Base Editing Process and the Roles of Translesion DNA Polymerases. ACS Synth Biol 10(12):3353-3358 PMID: 34851089
- Denkiewicz-Kruk M, et al. (2020) Recombination and Pol ζ Rescue Defective DNA Replication upon Impaired CMG Helicase-Pol ε Interaction. Int J Mol Sci 21(24) PMID: 33322195
- Malik R, et al. (2020) Structure and mechanism of B-family DNA polymerase ζ specialized for translesion DNA synthesis. Nat Struct Mol Biol 27(10):913-924 PMID: 32807989
- Qi L, et al. (2019) Hydrogen peroxide, a potent inducer of global genomic instability. Curr Genet 65(4):913-917 PMID: 30963245
- Kiktev DA, et al. (2018) GC content elevates mutation and recombination rates in the yeast <i>Saccharomyces cerevisiae</i>. Proc Natl Acad Sci U S A 115(30):E7109-E7118 PMID: 29987035
- Szwajczak E, et al. (2018) The importance of an interaction network for proper DNA polymerase ζ heterotetramer activity. Curr Genet 64(3):575-580 PMID: 29189894
- Segovia R, et al. (2017) Hypermutation signature reveals a slippage and realignment model of translesion synthesis by Rev3 polymerase in cisplatin-treated yeast. Proc Natl Acad Sci U S A 114(10):2663-2668 PMID: 28223526
- Szwajczak E, et al. (2017) The CysB motif of Rev3p involved in the formation of the four-subunit DNA polymerase ζ is required for defective-replisome-induced mutagenesis. Mol Microbiol 106(4):659-672 PMID: 28941243
- Northam MR and Trujillo KM (2016) Histone H2B mono-ubiquitylation maintains genomic integrity at stalled replication forks. Nucleic Acids Res 44(19):9245-9255 PMID: 27458205
- Garbacz M, et al. (2015) Fidelity consequences of the impaired interaction between DNA polymerase epsilon and the GINS complex. DNA Repair (Amst) 29:23-35 PMID: 25758782
- Grabowska E, et al. (2014) Proper functioning of the GINS complex is important for the fidelity of DNA replication in yeast. Mol Microbiol 92(4):659-80 PMID: 24628792
- Alexander MP, et al. (2013) High levels of transcription stimulate transversions at GC base pairs in yeast. Environ Mol Mutagen 54(1):44-53 PMID: 23055242
- Tang W, et al. (2013) Genomic deletions and point mutations induced in Saccharomyces cerevisiae by the trinucleotide repeats (GAA·TTC) associated with Friedreich's ataxia. DNA Repair (Amst) 12(1):10-7 PMID: 23182423
- Baruffini E, et al. (2012) Overexpression of DNA polymerase zeta reduces the mitochondrial mutability caused by pathological mutations in DNA polymerase gamma in yeast. PLoS One 7(3):e34322 PMID: 22470557
- Kraszewska J, et al. (2012) Defect of Dpb2p, a noncatalytic subunit of DNA polymerase ɛ, promotes error prone replication of undamaged chromosomal DNA in Saccharomyces cerevisiae. Mutat Res 737(1-2):34-42 PMID: 22709919
- Stone JE, et al. (2012) DNA polymerase zeta generates clustered mutations during bypass of endogenous DNA lesions in Saccharomyces cerevisiae. Environ Mol Mutagen 53(9):777-86 PMID: 22965922
- Stone JE, et al. (2011) Lesion bypass by S. cerevisiae Pol ζ alone. DNA Repair (Amst) 10(8):826-34 PMID: 21622032
- Northam MR, et al. (2010) Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiae. Genetics 184(1):27-42 PMID: 19841096
- Acharya N, et al. (2009) Yeast Rev1 protein promotes complex formation of DNA polymerase zeta with Pol32 subunit of DNA polymerase delta. Proc Natl Acad Sci U S A 106(24):9631-6 PMID: 19487673
- Lehner K and Jinks-Robertson S (2009) The mismatch repair system promotes DNA polymerase zeta-dependent translesion synthesis in yeast. Proc Natl Acad Sci U S A 106(14):5749-54 PMID: 19307574
- Pagès V, et al. (2009) Role of DNA damage-induced replication checkpoint in promoting lesion bypass by translesion synthesis in yeast. Genes Dev 23(12):1438-49 PMID: 19528320
- D'Souza S, et al. (2008) Novel conserved motifs in Rev1 C-terminus are required for mutagenic DNA damage tolerance. DNA Repair (Amst) 7(9):1455-70 PMID: 18603483
- Gan GN, et al. (2008) DNA polymerase zeta (pol zeta) in higher eukaryotes. Cell Res 18(1):174-83 PMID: 18157155
- Howell CA, et al. (2008) Substitution of a residue contacting the triphosphate moiety of the incoming nucleotide increases the fidelity of yeast DNA polymerase zeta. Nucleic Acids Res 36(5):1731-40 PMID: 18263611
- Yang Y, et al. (2008) Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae. PLoS Genet 4(11):e1000264 PMID: 19023402
- Collins NS, et al. (2007) Rev1 enhances CAG.CTG repeat stability in Saccharomyces cerevisiae. DNA Repair (Amst) 6(1):38-44 PMID: 16979389
- Sakamoto AN, et al. (2007) Mutator alleles of yeast DNA polymerase zeta. DNA Repair (Amst) 6(12):1829-38 PMID: 17715002
- Hirano Y and Sugimoto K (2006) ATR homolog Mec1 controls association of DNA polymerase zeta-Rev1 complex with regions near a double-strand break. Curr Biol 16(6):586-90 PMID: 16546083
- Kolas NK and Durocher D (2006) DNA repair: DNA polymerase zeta and Rev1 break in. Curr Biol 16(8):R296-9 PMID: 16631579
- Northam MR, et al. (2006) A novel function of DNA polymerase zeta regulated by PCNA. EMBO J 25(18):4316-25 PMID: 16957771
- Waters LS and Walker GC (2006) The critical mutagenic translesion DNA polymerase Rev1 is highly expressed during G(2)/M phase rather than S phase. Proc Natl Acad Sci U S A 103(24):8971-6 PMID: 16751278
- Zhang H, et al. (2006) Saccharomyces cerevisiae polymerase zeta functions in mitochondria. Genetics 172(4):2683-8 PMID: 16452144
- Zhang H, et al. (2006) The Saccharomyces cerevisiae rev6-1 mutation, which inhibits both the lesion bypass and the recombination mode of DNA damage tolerance, is an allele of POL30, encoding proliferating cell nuclear antigen. Genetics 173(4):1983-9 PMID: 16783012
- Zhong X, et al. (2006) The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins. Nucleic Acids Res 34(17):4731-42 PMID: 16971464
- Auerbach P, et al. (2005) Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA. Proc Natl Acad Sci U S A 102(49):17711-6 PMID: 16314579
- Garg P and Burgers PM (2005) Ubiquitinated proliferating cell nuclear antigen activates translesion DNA polymerases eta and REV1. Proc Natl Acad Sci U S A 102(51):18361-6 PMID: 16344468
- Garg P, et al. (2005) Proliferating cell nuclear antigen promotes translesion synthesis by DNA polymerase zeta. J Biol Chem 280(25):23446-50 PMID: 15879599
- Gibbs PE, et al. (2005) The relative roles in vivo of Saccharomyces cerevisiae Pol eta, Pol zeta, Rev1 protein and Pol32 in the bypass and mutation induction of an abasic site, T-T (6-4) photoadduct and T-T cis-syn cyclobutane dimer. Genetics 169(2):575-82 PMID: 15520252
- Sabbioneda S, et al. (2005) The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae. J Biol Chem 280(46):38657-65 PMID: 16169844
- Zhang H and Lawrence CW (2005) The error-free component of the RAD6/RAD18 DNA damage tolerance pathway of budding yeast employs sister-strand recombination. Proc Natl Acad Sci U S A 102(44):15954-9 PMID: 16247017
- Guo D, et al. (2004) Translesion synthesis of acetylaminofluorene-dG adducts by DNA polymerase zeta is stimulated by yeast Rev1 protein. Nucleic Acids Res 32(3):1122-30 PMID: 14960722
- Washington MT, et al. (2004) Efficient and error-free replication past a minor-groove N2-guanine adduct by the sequential action of yeast Rev1 and DNA polymerase zeta. Mol Cell Biol 24(16):6900-6 PMID: 15282292
- Diaz M, et al. (2003) Decreased frequency and highly aberrant spectrum of ultraviolet-induced mutations in the hprt gene of mouse fibroblasts expressing antisense RNA to DNA polymerase zeta. Mol Cancer Res 1(11):836-47 PMID: 14517346
- Johnson RE, et al. (2003) Yeast DNA polymerase zeta (zeta) is essential for error-free replication past thymine glycol. Genes Dev 17(1):77-87 PMID: 12514101
- Sakai W, et al. (2003) Isolation and genetic characterization of the Neurospora crassa REV1 and REV7 homologs: evidence for involvement in damage-induced mutagenesis. DNA Repair (Amst) 2(3):337-46 PMID: 12547396
- Simpson LJ and Sale JE (2003) Rev1 is essential for DNA damage tolerance and non-templated immunoglobulin gene mutation in a vertebrate cell line. EMBO J 22(7):1654-64 PMID: 12660171
- Sonoda E, et al. (2003) Multiple roles of Rev3, the catalytic subunit of polzeta in maintaining genome stability in vertebrates. EMBO J 22(12):3188-97 PMID: 12805232
- Zhu F and Zhang M (2003) DNA polymerase zeta: new insight into eukaryotic mutagenesis and mammalian embryonic development. World J Gastroenterol 9(6):1165-9 PMID: 12800216
- Haracska L, et al. (2002) Yeast Rev1 protein is a G template-specific DNA polymerase. J Biol Chem 277(18):15546-51 PMID: 11850424
- Lawrence CW (2002) Cellular roles of DNA polymerase zeta and Rev1 protein. DNA Repair (Amst) 1(6):425-35 PMID: 12509231
- Murakumo Y (2002) The property of DNA polymerase zeta: REV7 is a putative protein involved in translesion DNA synthesis and cell cycle control. Mutat Res 510(1-2):37-44 PMID: 12459441
- Simhadri S, et al. (2002) Benzo[a]pyrene diol epoxide-deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase zeta in vitro. Mutat Res 508(1-2):137-45 PMID: 12379469
- Van Sloun PP, et al. (2002) Involvement of mouse Rev3 in tolerance of endogenous and exogenous DNA damage. Mol Cell Biol 22(7):2159-69 PMID: 11884603
- Eeken JC, et al. (2001) Isolation and genetic characterisation of the Drosophila homologue of (SCE)REV3, encoding the catalytic subunit of DNA polymerase zeta. Mutat Res 485(3):237-53 PMID: 11267835
- Guo D, et al. (2001) Translesion synthesis by yeast DNA polymerase zeta from templates containing lesions of ultraviolet radiation and acetylaminofluorene. Nucleic Acids Res 29(13):2875-83 PMID: 11433034
- Lawrence CW and Maher VM (2001) Eukaryotic mutagenesis and translesion replication dependent on DNA polymerase zeta and Rev1 protein. Biochem Soc Trans 29(Pt 2):187-91 PMID: 11356151
- Lawrence CW and Maher VM (2001) Mutagenesis in eukaryotes dependent on DNA polymerase zeta and Rev1p. Philos Trans R Soc Lond B Biol Sci 356(1405):41-6 PMID: 11205328
- Murakumo Y, et al. (2001) Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7. J Biol Chem 276(38):35644-51 PMID: 11485998
- Gibbs PE, et al. (2000) The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light. Proc Natl Acad Sci U S A 97(8):4186-91 PMID: 10760286
- McHugh PJ, et al. (2000) Repair of intermediate structures produced at DNA interstrand cross-links in Saccharomyces cerevisiae. Mol Cell Biol 20(10):3425-33 PMID: 10779332
- Murakumo Y, et al. (2000) A human REV7 homolog that interacts with the polymerase zeta catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2. J Biol Chem 275(6):4391-7 PMID: 10660610
- Rajpal DK, et al. (2000) Alteration of ultraviolet-induced mutagenesis in yeast through molecular modulation of the REV3 and REV7 gene expression. Mutat Res 461(2):133-43 PMID: 11018586
- Lin W, et al. (1999) A full-length cDNA of hREV3 is predicted to encode DNA polymerase zeta for damage-induced mutagenesis in humans. Mutat Res 433(2):89-98 PMID: 10102035
- Van Sloun PP, et al. (1999) Molecular cloning, expression and chromosomal localisation of the mouse Rev3l gene, encoding the catalytic subunit of polymerase zeta. Mutat Res 433(2):109-16 PMID: 10102037
- Baynton K, et al. (1998) Analysis of damage tolerance pathways in Saccharomyces cerevisiae: a requirement for Rev3 DNA polymerase in translesion synthesis. Mol Cell Biol 18(2):960-6 PMID: 9447993
- Burgers PM (1998) Eukaryotic DNA polymerases in DNA replication and DNA repair. Chromosoma 107(4):218-27 PMID: 9745046
- Gibbs PE, et al. (1998) A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta. Proc Natl Acad Sci U S A 95(12):6876-80 PMID: 9618506
- Johnson RE, et al. (1998) Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites. Genes Dev 12(19):3137-43 PMID: 9765213
- Xiao W, et al. (1998) Identification, chromosomal mapping and tissue-specific expression of hREV3 encoding a putative human DNA polymerase zeta. Carcinogenesis 19(5):945-9 PMID: 9635887
- Holbeck SL and Strathern JN (1997) A role for REV3 in mutagenesis during double-strand break repair in Saccharomyces cerevisiae. Genetics 147(3):1017-24 PMID: 9383049
- Wood RD and Shivji MK (1997) Which DNA polymerases are used for DNA-repair in eukaryotes? Carcinogenesis 18(4):605-10 PMID: 9111189
- Lawrence CW and Hinkle DC (1996) DNA polymerase zeta and the control of DNA damage induced mutagenesis in eukaryotes. Cancer Surv 28:21-31 PMID: 8977026
- Nelson JR, et al. (1996) Thymine-thymine dimer bypass by yeast DNA polymerase zeta. Science 272(5268):1646-9 PMID: 8658138