Gene Ontology Help

Global genome repair CUL3-RAD7-RAD16-ELC1 ubiquitin ligase complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

A ubiquitin ligase complex required for optimal nucleotide excision repair following UV-induced DNA damage. Ubiquinates the DNA repair protein RAD4 (P14736), targeting it for degradation by the 26S proteasome following UV radiation. de novo protein synthesis subsequently restores RAD4 to pre-irradiation levels.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

acyltransferase activity, transferase activity, DNA damage response, DNA metabolic process, DNA repair, catabolic process, cellular nitrogen compound metabolic process, proteolysis involved in protein catabolic process, response to stress, Cul3-RING ubiquitin ligase complex, ubiquitin ligase complex