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General transcription factor TFIIIB complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Transcription factor complex required for Pol III transcription complex (CPX-2660) assembly which transcribes short noncoding RNA genes. Cooperates with TFIIIC (CPX-1656) to recruit Pol III to different types of gene promoters and form the preinitiation complex (PIC). In the case of PIC formation at transfer DNA (tDNA) genes, TFIIIC recognizes the gene-internal box A and B elements, while TFIIIB localizes further upstream. TFIIIA (P39933) is required only for the transcription of 5S rRNA, where it recognizes the gene-internal control element, box C, to further recruit TFIIIC and TFIIIB. Once assembled upstream of the start site, TFIIIB generates a significant DNA distortion of the class III gene promoter through the SPT15 and BDP1 subunits.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

DNA binding, cellular component assembly, protein-containing complex assembly