Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
6 entries for 3 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| CAT2 | chemical compound accumulation: decreased | classical genetics | overexpression Allele: CAT2-mit mutant Cat2p localized to mitochondria only | Other | ethyl acetate | Cordente AG, et al. (2007) PMID:17156120 | |
| EAT1 | chemical compound accumulation: decreased | classical genetics | null Allele: eat1-Δ | Other | ethyl acetate | Details: ethyl acetate production reduced by at least 50% compared to wild type | Kruis AJ, et al. (2017) PMID:28356220 |
| ATF1 | chemical compound excretion: decreased | classical genetics | null Allele: atf1-Δ | Other | ethyl acetate | Details: relative levels reduced to about 65% that of the wildtype control | Fujii T, et al. (1996) |
| ATF2 | chemical compound excretion: decreased | classical genetics | null Allele: atf2-Δ | S288C | ethyl acetate | Details: 13% decrease relative to wildtype | Verstrepen KJ, et al. (2003) PMID:12957907 |
| ATF1 | chemical compound excretion: decreased | classical genetics | null Allele: atf1-Δ | S288C | ethyl acetate | Details: 40% decrease relative to wildtype | Verstrepen KJ, et al. (2003) PMID:12957907 |
| ATF1 | chemical compound excretion: increased | classical genetics | overexpression | Other | ethyl acetate | Details: 9-fold increase relative to vector control | Fujii T, et al. (1994) PMID:8085822 |
This diagram displays Gene Ontology terms (green), phenotypes (blue), and macromolecular complexes (yellow) that are shared between the given chemical (black) and other chemicals (purple). The shared GO terms, phenotypes or complexes can be visualized separately using the radio button at the bottom of the graph.