Ribeiro MO, et al. (2025) N88S seipin-related seipinopathy is a lipidopathy associated with loss of iron homeostasis. Cell Commun Signal 23(1):10 PMID:39773523
Costa V and Teixeira V (2024) Vacuolar ATPase-mediated regulation of neutral lipid dynamics: Insights into lipid droplet homeostasis and stress response mechanisms. Biochim Biophys Acta Mol Cell Biol Lipids 1869(3):159465 PMID:38350538
Martins TS, et al. (2023) Iron Limitation Restores Autophagy and Increases Lifespan in the Yeast Model of Niemann-Pick Type C1. Int J Mol Sci 24(7) PMID:37047194
Nogueira V, et al. (2022) Causative links between ER stress and oxidative damage in a yeast model of human N88S seipinopathy. Free Radic Biol Med 192:165-181 PMID:36126862
Teixeira V, et al. (2021) Target of Rapamycin Complex 1 (TORC1), Protein Kinase A (PKA) and Cytosolic pH Regulate a Transcriptional Circuit for Lipid Droplet Formation. Int J Mol Sci 22(16) PMID:34445723
Martins TS, et al. (2018) The Hog1p kinase regulates Aft1p transcription factor to control iron accumulation. Biochim Biophys Acta Mol Cell Biol Lipids 1863(1):61-70 PMID:29032057
Vilaça R, et al. (2018) The ceramide activated protein phosphatase Sit4 impairs sphingolipid dynamics, mitochondrial function and lifespan in a yeast model of Niemann-Pick type C1. Biochim Biophys Acta Mol Basis Dis 1864(1):79-88 PMID:28988886
Teixeira V and Costa V (2016) Unraveling the role of the Target of Rapamycin signaling in sphingolipid metabolism. Prog Lipid Res 61:109-33 PMID:26703187
Teixeira V, et al. (2016) Ceramide signaling targets the PP2A-like protein phosphatase Sit4p to impair vacuolar function, vesicular trafficking and autophagy in Isc1p deficient cells. Biochim Biophys Acta 1861(1):21-33 PMID:26477382
Teixeira V, et al. (2015) Ceramide signalling impinges on Sit4p and Hog1p to promote mitochondrial fission and mitophagy in Isc1p-deficient cells. Cell Signal 27(9):1840-9 PMID:26079297
Vilaça R, et al. (2014) Sphingolipid signalling mediates mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of Niemann-Pick type C1. Mol Microbiol 91(3):438-51 PMID:24286211