Park S, et al. (2025) An adenine model of inborn metabolism errors alters TDP-43 aggregation and reduces its toxicity in yeast revealing insights into protein misfolding diseases. Microb Cell 12:119-130 PMID:40421380
Park S, et al. (2024) Expression of Wild-Type and Mutant Human TDP-43 in Yeast Inhibits TOROID (TORC1 Organized in Inhibited Domain) Formation and Autophagy Proportionally to the Levels of TDP-43 Toxicity. Int J Mol Sci 25(11) PMID:38892445
Park SK, et al. (2022) TDP-43 Toxicity in Yeast Is Associated with a Reduction in Autophagy, and Deletions of TIP41 and PBP1 Counteract These Effects. Viruses 14(10) PMID:36298819
Park SK, et al. (2021) Tumor suppressor protein p53 expressed in yeast can remain diffuse, form a prion, or form unstable liquid-like droplets. iScience 24(1):102000 PMID:33490908
Park S, et al. (2019) Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies. PLoS Genet 15(8):e1008308 PMID:31390360
Park SK, et al. (2019) Respiration Enhances TDP-43 Toxicity, but TDP-43 Retains Some Toxicity in the Absence of Respiration. J Mol Biol 431(10):2050-2059 PMID:30905713
Park SK, et al. (2018) Overexpression of a conserved HSP40 chaperone reduces toxicity of several neurodegenerative disease proteins. Prion 12(1):16-22 PMID:29308690
Park SK, et al. (2017) Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis. PLoS Genet 13(5):e1006805 PMID:28531192
Park SK, et al. (2016) Inhibition of Aβ42 oligomerization in yeast by a PICALM ortholog and certain FDA approved drugs. Microb Cell 3(2):53-64 PMID:28357335
Yang Z, et al. (2014) Prion-promoted phosphorylation of heterologous amyloid is coupled with ubiquitin-proteasome system inhibition and toxicity. Mol Microbiol 93(5):1043-56 PMID:25039275
Derkatch IL and Liebman SW (2013) The story of stolen chaperones: how overexpression of Q/N proteins cures yeast prions. Prion 7(4):294-300 PMID:23924684
Yang Z, et al. (2013) Heterologous gln/asn-rich proteins impede the propagation of yeast prions by altering chaperone availability. PLoS Genet 9(1):e1003236 PMID:23358669
Mathur V, et al. (2012) Localization of HET-S to the cell periphery, not to [Het-s] aggregates, is associated with [Het-s]-HET-S toxicity. Mol Cell Biol 32(1):139-53 PMID:22037764
Chernova TA, et al. (2011) Prion induction by the short-lived, stress-induced protein Lsb2 is regulated by ubiquitination and association with the actin cytoskeleton. Mol Cell 43(2):242-52 PMID:21777813
Hong JY, et al. (2011) A new colour assay for [URE3] prion in a genetic background used to score for the [PSI⁺] prion. Yeast 28(7):555-60 PMID:21590810
Manogaran AL, et al. (2011) Prion formation and polyglutamine aggregation are controlled by two classes of genes. PLoS Genet 7(5):e1001386 PMID:21625618
Mathur V, et al. (2010) Analyzing the birth and propagation of two distinct prions, [PSI+] and [Het-s](y), in yeast. Mol Biol Cell 21(9):1449-61 PMID:20219972
Bagriantsev SN, et al. (2008) Variant-specific [PSI+] infection is transmitted by Sup35 polymers within [PSI+] aggregates with heterogeneous protein composition. Mol Biol Cell 19(6):2433-43 PMID:18353968
Patel BK and Liebman SW (2007) "Prion-proof" for [PIN+]: infection with in vitro-made amyloid aggregates of Rnq1p-(132-405) induces [PIN+]. J Mol Biol 365(3):773-82 PMID:17097676
Vitrenko YA, et al. (2007) Visualization of aggregation of the Rnq1 prion domain and cross-seeding interactions with Sup35NM. J Biol Chem 282(3):1779-87 PMID:17121829
Manogaran AL, et al. (2006) An engineered nonsense URA3 allele provides a versatile system to detect the presence, absence and appearance of the [PSI+] prion in Saccharomyces cerevisiae. Yeast 23(2):141-7 PMID:16491470
Bagriantsev S and Liebman SW (2004) Specificity of prion assembly in vivo. [PSI+] and [PIN+] form separate structures in yeast. J Biol Chem 279(49):51042-8 PMID:15465809
Bradley ME and Liebman SW (2004) The Sup35 domains required for maintenance of weak, strong or undifferentiated yeast [PSI+] prions. Mol Microbiol 51(6):1649-59 PMID:15009892
Derkatch IL, et al. (2004) Effects of Q/N-rich, polyQ, and non-polyQ amyloids on the de novo formation of the [PSI+] prion in yeast and aggregation of Sup35 in vitro. Proc Natl Acad Sci U S A 101(35):12934-9 PMID:15326312
Velichutina IV, et al. (2001) Genetic interaction between yeast Saccharomyces cerevisiae release factors and the decoding region of 18 S rRNA. J Mol Biol 305(4):715-27 PMID:11162087
Zhou P, et al. (2001) The relationship between visible intracellular aggregates that appear after overexpression of Sup35 and the yeast prion-like elements [PSI(+)] and [PIN(+)]. Mol Microbiol 39(1):37-46 PMID:11123686
Dresios J, et al. (2000) Yeast ribosomal protein L24 affects the kinetics of protein synthesis and ribosomal protein L39 improves translational accuracy, while mutants lacking both remain viable. Biochemistry 39(24):7236-44 PMID:10852723
Velichutina IV, et al. (2000) Mutations in helix 27 of the yeast Saccharomyces cerevisiae 18S rRNA affect the function of the decoding center of the ribosome. RNA 6(8):1174-84 PMID:10943896
Burck CL, et al. (1999) Translational suppressors and antisuppressors alter the efficiency of the Ty1 programmed translational frameshift. RNA 5(11):1451-7 PMID:10580473
Derkatch IL, et al. (1999) The PNM2 mutation in the prion protein domain of SUP35 has distinct effects on different variants of the [PSI+] prion in yeast. Curr Genet 35(2):59-67 PMID:10079323
Zhou P, et al. (1999) The yeast non-Mendelian factor [ETA+] is a variant of [PSI+], a prion-like form of release factor eRF3. EMBO J 18(5):1182-91 PMID:10064585
Derkatch IL, et al. (1998) Overexpression of the SUP45 gene encoding a Sup35p-binding protein inhibits the induction of the de novo appearance of the [PSI+] prion. Proc Natl Acad Sci U S A 95(5):2400-5 PMID:9482897
Qian Z, et al. (1998) Yeast Ty1 retrotransposition is stimulated by a synergistic interaction between mutations in chromatin assembly factor I and histone regulatory proteins. Mol Cell Biol 18(8):4783-92 PMID:9671488
Derkatch IL, et al. (1997) Genetic and environmental factors affecting the de novo appearance of the [PSI+] prion in Saccharomyces cerevisiae. Genetics 147(2):507-19 PMID:9335589
Huang H, et al. (1997) The ubiquitin-conjugating enzyme Rad6 (Ubc2) is required for silencing in Saccharomyces cerevisiae. Mol Cell Biol 17(11):6693-9 PMID:9343433
Chernoff YO, et al. (1996) The translational function of nucleotide C1054 in the small subunit rRNA is conserved throughout evolution: genetic evidence in yeast. Proc Natl Acad Sci U S A 93(6):2517-22 PMID:8637906
Liu R and Liebman SW (1996) A translational fidelity mutation in the universally conserved sarcin/ricin domain of 25S yeast ribosomal RNA. RNA 2(3):254-63 PMID:8608449
Anthony RA and Liebman SW (1995) Alterations in ribosomal protein RPS28 can diversely affect translational accuracy in Saccharomyces cerevisiae. Genetics 140(4):1247-58 PMID:7498767
Chernoff YO, et al. (1995) Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]. Science 268(5212):880-4 PMID:7754373
Lindquist S, et al. (1995) The role of Hsp104 in stress tolerance and [PSI+] propagation in Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol 60:451-60 PMID:8824419
Vincent A, et al. (1994) The yeast translational allosuppressor, SAL6: a new member of the PP1-like phosphatase family with a long serine-rich N-terminal extension. Genetics 138(3):597-608 PMID:7851758
Liebman SW and Newnam G (1993) A ubiquitin-conjugating enzyme, RAD6, affects the distribution of Ty1 retrotransposon integration positions. Genetics 133(3):499-508 PMID:8384143
Sutton PR and Liebman SW (1992) Rearrangements occurring adjacent to a single Ty1 yeast retrotransposon in the presence and absence of full-length Ty1 transcription. Genetics 131(4):833-50 PMID:1325387
Vincent A and Liebman SW (1992) The yeast omnipotent suppressor SUP46 encodes a ribosomal protein which is a functional and structural homolog of the Escherichia coli S4 ram protein. Genetics 132(2):375-86 PMID:1427034
All-Robyn JA, et al. (1990) Sequence and functional similarity between a yeast ribosomal protein and the Escherichia coli S5 ram protein. Mol Cell Biol 10(12):6544-53 PMID:2247072
Picologlou S, et al. (1988) The same configuration of Ty elements promotes different types and frequencies of rearrangements in different yeast strains. Mol Gen Genet 211(2):272-81 PMID:2832703
Song JM and Liebman SW (1987) Allosuppressors that enhance the efficiency of omnipotent suppressors in Saccharomyces cerevisiae. Genetics 115(3):451-60 PMID:3552876
Song JM and Liebman SW (1985) Interaction of UAG suppressors and omnipotent suppressors in Saccharomyces cerevisiae. J Bacteriol 161(2):778-80 PMID:3881411
Liebman SW and All-Robyn JA (1984) A non-Mendelian factor, [eta(+)], causes lethality of yeast omnipotent-suppressor strains. Curr Genet 8(8):567-73 PMID:24177995
Downs KM, et al. (1983) Analysis of the effect of radiation repair mutations on the DEL1 mutator region of Saccharomyces cerevisiae. Curr Genet 7(1):57-61 PMID:24173119
Liebman SW and Cavenagh MM (1981) 4OS ribosomal protein from a Saccharomyces cerevisiae antisuppressor mutant exhibiting a unique 2D gel pattern. Curr Genet 3(1):27-9 PMID:24189949
Liebman SW and Downs KM (1980) The RAD52 gene is not required for the function of the DEL1 mutator gene in Saccharomyces cerevisiae. Mol Gen Genet 179(3):703-5 PMID:7003305
Liebman SW, et al. (1980) Isolation and properties of an antisuppressor in Saccharomyces cerevisiae specific for an omnipotent suppressor. J Bacteriol 143(3):1527-9 PMID:6997279
Sherman F, et al. (1975) A deletion map of cyc1 mutants and its correspondence to mutationally altered iso-1-cytochromes c of yeast. Genetics 81(1):51-73 PMID:173620