Klassen R, et al. (2023) Mismatch repair operates at the replication fork in direct competition with mismatch extension by DNA polymerase δ. J Biol Chem 299(4):104598 PMID:36898578
Matos GS, et al. (2023) Lipidome remodeling in response to nutrient replenishment requires the tRNA modifier Deg1/Pus3 in yeast. Mol Microbiol 120(6):893-905 PMID:37864403
Ütkür K, et al. (2023)DPH1 Gene Mutations Identify a Candidate SAM Pocket in Radical Enzyme Dph1•Dph2 for Diphthamide Synthesis on EF2. Biomolecules 13(11) PMID:38002337
Khonsari B, et al. (2021) Role of SSD1 in Phenotypic Variation of Saccharomyces cerevisiae Strains Lacking DEG1-Dependent Pseudouridylation. Int J Mol Sci 22(16) PMID:34445460
Bruch A, et al. (2020) Misactivation of multiple starvation responses in yeast by loss of tRNA modifications. Nucleic Acids Res 48(13):7307-7320 PMID:32484543
Khonsari B and Klassen R (2020) Impact of Pus1 Pseudouridine Synthase on Specific Decoding Events in Saccharomyces cerevisiae. Biomolecules 10(5) PMID:32392804
Klassen R, et al. (2020) Induction of protein aggregation and starvation response by tRNA modification defects. Curr Genet 66(6):1053-1057 PMID:32860511
Pollo-Oliveira L, et al. (2020) Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast. Biomolecules 10(2) PMID:32085421
Schäck MA, et al. (2020) Eukaryotic life without tQCUG: the role of Elongator-dependent tRNA modifications in Dictyostelium discoideum. Nucleic Acids Res 48(14):7899-7913 PMID:32609816
Bozaquel-Morais BL, et al. (2018) Protein Phosphatase Sit4 Affects Lipid Droplet Synthesis and Soraphen A Resistance Independent of Its Role in Regulating Elongator Dependent tRNA Modification. Biomolecules 8(3) PMID:29997346
Klassen R and Schaffrath R (2018) Collaboration of tRNA modifications and elongation factor eEF1A in decoding and nonsense suppression. Sci Rep 8(1):12749 PMID:30143741
Sokołowski M, et al. (2018) Cooperativity between different tRNA modifications and their modification pathways. Biochim Biophys Acta Gene Regul Mech 1861(4):409-418 PMID:29222069
Klassen R and Schaffrath R (2017) Role of Pseudouridine Formation by Deg1 for Functionality of Two Glutamine Isoacceptor tRNAs. Biomolecules 7(1) PMID:28134782
Schaffrath R and Klassen R (2017) Combined tRNA modification defects impair protein homeostasis and synthesis of the yeast prion protein Rnq1. Prion 11(1):48-53 PMID:28281930
Klassen R, et al. (2016) tRNA anticodon loop modifications ensure protein homeostasis and cell morphogenesis in yeast. Nucleic Acids Res 44(22):10946-10959 PMID:27496282
Johnson RE, et al. (2015) A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands. Mol Cell 59(2):163-175 PMID:26145172
Jüdes A, et al. (2015) Urmylation and tRNA thiolation functions of ubiquitin-like Uba4·Urm1 systems are conserved from yeast to man. FEBS Lett 589(8):904-9 PMID:25747390
Klassen R, et al. (2015) Loss of anticodon wobble uridine modifications affects tRNA(Lys) function and protein levels in Saccharomyces cerevisiae. PLoS One 10(3):e0119261 PMID:25747122
Scheidt V, et al. (2014) Loss of wobble uridine modification in tRNA anticodons interferes with TOR pathway signaling. Microb Cell 1(12):416-424 PMID:28357221
Wemhoff S, et al. (2014) Site-directed mutagenesis of the heterotrimeric killer toxin zymocin identifies residues required for early steps in toxin action. Appl Environ Microbiol 80(20):6549-59 PMID:25128337
Meineke B, et al. (2012) A fungal anticodon nuclease ribotoxin exploits a secondary cleavage site to evade tRNA repair. RNA 18(9):1716-24 PMID:22836353
Acharya N, et al. (2011) PCNA binding domains in all three subunits of yeast DNA polymerase δ modulate its function in DNA replication. Proc Natl Acad Sci U S A 108(44):17927-32 PMID:22003126
Paluszynski JP, et al. (2008) Genetic prerequisites for additive or synergistic actions of 5-fluorocytosine and fluconazole in baker's yeast. Microbiology (Reading) 154(Pt 10):3154-3164 PMID:18832321
Klassen R, et al. (2007) Homologous recombination and the yKu70/80 complex exert opposite roles in resistance against the killer toxin from Pichia acaciae. DNA Repair (Amst) 6(12):1864-75 PMID:17765020
Klassen R, et al. (2006) Mating-type locus control of killer toxins from Kluyveromyces lactis and Pichia acaciae. FEMS Yeast Res 6(3):404-13 PMID:16630280
Paluszynski JP, et al. (2006) Various cytosine/adenine permease homologues are involved in the toxicity of 5-fluorocytosine in Saccharomyces cerevisiae. Yeast 23(9):707-15 PMID:16845689
Klassen R and Meinhardt F (2005) Induction of DNA damage and apoptosis in Saccharomyces cerevisiae by a yeast killer toxin. Cell Microbiol 7(3):393-401 PMID:15679842
Klassen R and Meinhardt F (2003) Structural and functional analysis of the killer element pPin1-3 from Pichia inositovora. Mol Genet Genomics 270(2):190-9 PMID:13680368