AboutBlogDownloadExploreHelpGet Data
Email Us Mastodon BlueSky Facebook LinkedIn YouTube
Saccharomyces Genome Database
  • Saccharomyces Genome Database
    Saccharomyces Genome Database
  • Menu
  • Analyze
    • Gene Lists
    • BLAST
    • Fungal BLAST
    • GO Term Finder
    • GO Slim Mapper
    • Pattern Matching
    • Design Primers
    • Restriction Site Mapper
  • Sequence
    • Download
    • Genome Browser
    • BLAST
    • Fungal BLAST
    • Gene/Sequence Resources
    • Reference Genome
      • Download Genome
      • Genome Snapshot
      • Chromosome History
      • Systematic Sequencing Table
      • Original Sequence Papers
    • Strains and Species
      • Variant Viewer
      • Align Strain Sequences
    • Resources
      • UniProtKB
      • InterPro (EBI)
      • HomoloGene (NCBI)
      • YGOB (Trinity College)
      • AlphaFold
  • Function
    • Gene Ontology
      • GO Term Finder
      • GO Slim Mapper
      • GO Slim Mapping File
    • Expression
    • Biochemical Pathways
    • Phenotypes
      • Browse All Phenotypes
    • Interactions
    • YeastGFP
    • Resources
      • GO Consortium
      • BioGRID (U. Toronto)
  • Literature
    • Full-text Search
    • New Yeast Papers
    • YeastBook
    • Resources
      • PubMed (NCBI)
      • PubMed Central (NCBI)
      • Google Scholar
  • Community
    • Community Forum
    • Colleague Information
      • Find a Colleague
      • Add or Update Info
      • Find a Yeast Lab
    • Education
    • Meetings
    • Nomenclature
      • Submit a Gene Registration
      • Gene Registry
      • Nomenclature Conventions
    • Methods and Reagents
      • Strains
    • Historical Data
      • Physical & Genetic Maps
      • Genetic Maps
      • Genetic Loci
      • ORFMap Chromosomes
      • Sequence
    • Submit Data
    • API
  • Info & Downloads
    • About
    • Blog
    • Downloads
    • Site Map
    • Help
  • Author: Kinzy TG
  • References

Author: Kinzy TG


References 61 references


No citations for this author.

Download References (.nbib)

  • Shin BS, et al. (2023) eEF2 diphthamide modification restrains spurious frameshifting to maintain translational fidelity. Nucleic Acids Res 51(13):6899-6913 PMID:37246715
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Mateyak MK, et al. (2021) Mutational analysis reveals potential phosphorylation sites in eukaryotic elongation factor 1A that are important for its activity. FEBS Lett 595(17):2208-2220 PMID:34293820
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Mateyak MK, et al. (2018) Demonstration of translation elongation factor 3 activity from a non-fungal species, Phytophthora infestans. PLoS One 13(1):e0190524 PMID:29300771
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Mateyak MK and Kinzy TG (2017) Breaking the Silos of Protein Synthesis. Trends Biochem Sci 42(8):587-588 PMID:28669455
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Dever TE, et al. (2016) Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae. Genetics 203(1):65-107 PMID:27183566
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Esposito AM and Kinzy TG (2014) In vivo [35S]-methionine incorporation. Methods Enzymol 536:55-64 PMID:24423266
    • SGD Paper
    • DOI full text
    • PubMed
  • Li Z, et al. (2014) Methylation of translation elongation factor 1A by the METTL10-like See1 methyltransferase facilitates tombusvirus replication in yeast and plants. Virology 448:43-54 PMID:24314635
    • SGD Paper
    • DOI full text
    • PubMed
  • Perez WB and Kinzy TG (2014) Translation elongation factor 1A mutants with altered actin bundling activity show reduced aminoacyl-tRNA binding and alter initiation via eIF2α phosphorylation. J Biol Chem 289(30):20928-38 PMID:24936063
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Sasikumar AN and Kinzy TG (2014) Mutations in the chromodomain-like insertion of translation elongation factor 3 compromise protein synthesis through reduced ATPase activity. J Biol Chem 289(8):4853-60 PMID:24379402
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Sasvari Z, et al. (2011) Synergistic roles of eukaryotic translation elongation factors 1Bγ and 1A in stimulation of tombusvirus minus-strand synthesis. PLoS Pathog 7(12):e1002438 PMID:22194687
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Visweswaraiah J, et al. (2011) Evidence that eukaryotic translation elongation factor 1A (eEF1A) binds the Gcn2 protein C terminus and inhibits Gcn2 activity. J Biol Chem 286(42):36568-79 PMID:21849502
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Esposito AM and Kinzy TG (2010) The eukaryotic translation elongation Factor 1Bgamma has a non-guanine nucleotide exchange factor role in protein metabolism. J Biol Chem 285(49):37995-8004 PMID:20926387
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Esposito AM, et al. (2010) Eukaryotic polyribosome profile analysis. J Vis Exp PMID:20567211
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Mateyak MK and Kinzy TG (2010) eEF1A: thinking outside the ribosome. J Biol Chem 285(28):21209-13 PMID:20444696
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Pittman YR, et al. (2009) Coordination of eukaryotic translation elongation factor 1A (eEF1A) function in actin organization and translation elongation by the guanine nucleotide exchange factor eEF1Balpha. J Biol Chem 284(7):4739-47 PMID:19095653
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Bockhorn J, et al. (2008) Genome-wide screen of Saccharomyces cerevisiae null allele strains identifies genes involved in selenomethionine resistance. Proc Natl Acad Sci U S A 105(46):17682-7 PMID:19004804
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Ozturk SB and Kinzy TG (2008) Guanine nucleotide exchange factor independence of the G-protein eEF1A through novel mutant forms and biochemical properties. J Biol Chem 283(34):23244-53 PMID:18562321
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Seitomer E, et al. (2008) Analysis of Saccharomyces cerevisiae null allele strains identifies a larger role for DNA damage versus oxidative stress pathways in growth inhibition by selenium. Mol Nutr Food Res 52(11):1305-15 PMID:18496816
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Galkin O, et al. (2007) Roles of the negatively charged N-terminal extension of Saccharomyces cerevisiae ribosomal protein S5 revealed by characterization of a yeast strain containing human ribosomal protein S5. RNA 13(12):2116-28 PMID:17901157
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Gromadski KB, et al. (2007) Kinetics of the interactions between yeast elongation factors 1A and 1Balpha, guanine nucleotides, and aminoacyl-tRNA. J Biol Chem 282(49):35629-37 PMID:17925388
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Gross SR and Kinzy TG (2007) Improper organization of the actin cytoskeleton affects protein synthesis at initiation. Mol Cell Biol 27(5):1974-89 PMID:17178834
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Hampsey M and Kinzy TG (2007) Synchronicity: policing multiple aspects of gene expression by Ctk1. Genes Dev 21(11):1288-91 PMID:17545464
    • SGD Paper
    • DOI full text
    • PubMed
  • Plant EP, et al. (2007) Differentiating between near- and non-cognate codons in Saccharomyces cerevisiae. PLoS One 2(6):e517 PMID:17565370
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Anand M, et al. (2006) Domain and nucleotide dependence of the interaction between Saccharomyces cerevisiae translation elongation factors 3 and 1A. J Biol Chem 281(43):32318-26 PMID:16954224
    • SGD Paper
    • DOI full text
    • PubMed
  • Andersen CB, et al. (2006) Structure of eEF3 and the mechanism of transfer RNA release from the E-site. Nature 443(7112):663-8 PMID:16929303
    • SGD Paper
    • DOI full text
    • PubMed
  • Chatterjee I, et al. (2006) Rapid depletion of mutant eukaryotic initiation factor 5A at restrictive temperature reveals connections to actin cytoskeleton and cell cycle progression. Mol Genet Genomics 275(3):264-76 PMID:16408210
    • SGD Paper
    • DOI full text
    • PubMed
  • Ortiz PA, et al. (2006) Translation elongation factor 2 anticodon mimicry domain mutants affect fidelity and diphtheria toxin resistance. J Biol Chem 281(43):32639-48 PMID:16950777
    • SGD Paper
    • DOI full text
    • PubMed
  • Ozturk SB, et al. (2006) Unique classes of mutations in the Saccharomyces cerevisiae G-protein translation elongation factor 1A suppress the requirement for guanine nucleotide exchange. Genetics 174(2):651-63 PMID:16951075
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Pittman YR, et al. (2006) Mg2+ and a key lysine modulate exchange activity of eukaryotic translation elongation factor 1B alpha. J Biol Chem 281(28):19457-68 PMID:16675455
    • SGD Paper
    • DOI full text
    • PubMed
  • Chuang SM, et al. (2005) Proteasome-mediated degradation of cotranslationally damaged proteins involves translation elongation factor 1A. Mol Cell Biol 25(1):403-13 PMID:15601860
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Gross SR and Kinzy TG (2005) Translation elongation factor 1A is essential for regulation of the actin cytoskeleton and cell morphology. Nat Struct Mol Biol 12(9):772-8 PMID:16116436
    • SGD Paper
    • DOI full text
    • PubMed
  • Magazinnik T, et al. (2005) Interplay between GCN2 and GCN4 expression, translation elongation factor 1 mutations and translational fidelity in yeast. Nucleic Acids Res 33(14):4584-92 PMID:16100380
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Ortiz PA and Kinzy TG (2005) Dominant-negative mutant phenotypes and the regulation of translation elongation factor 2 levels in yeast. Nucleic Acids Res 33(18):5740-8 PMID:16214807
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Andersen CF, et al. (2004) Purification and crystallization of the yeast translation elongation factor eEF3. Acta Crystallogr D Biol Crystallogr 60(Pt 7):1304-7 PMID:15213400
    • SGD Paper
    • DOI full text
    • PubMed
  • Olarewaju O, et al. (2004) The translation elongation factor eEF1B plays a role in the oxidative stress response pathway. RNA Biol 1(2):89-94 PMID:17179749
    • SGD Paper
    • DOI full text
    • PubMed
  • Anand M, et al. (2003) Functional interactions between yeast translation eukaryotic elongation factor (eEF) 1A and eEF3. J Biol Chem 278(9):6985-91 PMID:12493761
    • SGD Paper
    • DOI full text
    • PubMed
  • Jeppesen MG, et al. (2003) The crystal structure of the glutathione S-transferase-like domain of elongation factor 1Bgamma from Saccharomyces cerevisiae. J Biol Chem 278(47):47190-8 PMID:12972429
    • SGD Paper
    • DOI full text
    • PubMed
  • Jørgensen R, et al. (2003) Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase. Nat Struct Biol 10(5):379-85 PMID:12692531
    • SGD Paper
    • DOI full text
    • PubMed
  • Pomerening JR, et al. (2003) Mutation of a conserved CDK site converts a metazoan Elongation Factor 1Bbeta subunit into a replacement for yeast eEF1Balpha. Mol Genet Genomics 269(6):776-88 PMID:12898219
    • SGD Paper
    • DOI full text
    • PubMed
  • Valente L and Kinzy TG (2003) Yeast as a sensor of factors affecting the accuracy of protein synthesis. Cell Mol Life Sci 60(10):2115-30 PMID:14618259
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Carr-Schmid A, et al. (2002) Novel G-protein complex whose requirement is linked to the translational status of the cell. Mol Cell Biol 22(8):2564-74 PMID:11909951
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Jørgensen R, et al. (2002) Purification and crystallization of the yeast elongation factor eEF2. Acta Crystallogr D Biol Crystallogr 58(Pt 4):712-5 PMID:11914505
    • SGD Paper
    • DOI full text
    • PubMed
  • Kandl KA, et al. (2002) Identification of a role for actin in translational fidelity in yeast. Mol Genet Genomics 268(1):10-8 PMID:12242494
    • SGD Paper
    • DOI full text
    • PubMed
  • Anand M, et al. (2001) Translation elongation factor 1 functions in the yeast Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol 66:439-48 PMID:12762046
    • SGD Paper
    • DOI full text
    • PubMed
  • Andersen GR, et al. (2001) Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex. Nat Struct Biol 8(6):531-4 PMID:11373622
    • SGD Paper
    • DOI full text
    • PubMed
  • Munshi R, et al. (2001) Overexpression of translation elongation factor 1A affects the organization and function of the actin cytoskeleton in yeast. Genetics 157(4):1425-36 PMID:11290701
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Pedersen L, et al. (2001) Crystallization of the yeast elongation factor complex eEF1A-eEF1B alpha. Acta Crystallogr D Biol Crystallogr 57(Pt 1):159-61 PMID:11134944
    • SGD Paper
    • DOI full text
    • PubMed
  • Ruiz-Echevarria MJ, et al. (2001) Characterization of a general stabilizer element that blocks deadenylation-dependent mRNA decay. J Biol Chem 276(33):30995-1003 PMID:11423548
    • SGD Paper
    • DOI full text
    • PubMed
  • Andersen GR, et al. (2000) Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Balpha. Mol Cell 6(5):1261-6 PMID:11106763
    • SGD Paper
    • DOI full text
    • PubMed
  • Lee JH, et al. (2000) Hsl7p, the yeast homologue of human JBP1, is a protein methyltransferase. Biochem Biophys Res Commun 274(1):105-11 PMID:10903903
    • SGD Paper
    • DOI full text
    • PubMed
  • Carr-Schmid A, et al. (1999) Mutations in a GTP-binding motif of eukaryotic elongation factor 1A reduce both translational fidelity and the requirement for nucleotide exchange. J Biol Chem 274(42):30297-302 PMID:10514524
    • SGD Paper
    • DOI full text
    • PubMed
  • Carr-Schmid A, et al. (1999) Mutations in elongation factor 1beta, a guanine nucleotide exchange factor, enhance translational fidelity. Mol Cell Biol 19(8):5257-66 PMID:10409717
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Cui Y, et al. (1999) Mutations in the MOF2/SUI1 gene affect both translation and nonsense-mediated mRNA decay. RNA 5(6):794-804 PMID:10376878
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Cui Y, et al. (1998) The Mof2/Sui1 protein is a general monitor of translational accuracy. Mol Cell Biol 18(3):1506-16 PMID:9488467
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Asano K, et al. (1997) Conservation and diversity of eukaryotic translation initiation factor eIF3. J Biol Chem 272(2):1101-9 PMID:8995409
    • SGD Paper
    • DOI full text
    • PubMed
  • Dinman JD and Kinzy TG (1997) Translational misreading: mutations in translation elongation factor 1alpha differentially affect programmed ribosomal frameshifting and drug sensitivity. RNA 3(8):870-81 PMID:9257646
    • SGD Paper
    • PMC full text
    • PubMed
  • Kinzy TG and Woolford JL (1995) Increased expression of Saccharomyces cerevisiae translation elongation factor 1 alpha bypasses the lethality of a TEF5 null allele encoding elongation factor 1 beta. Genetics 141(2):481-9 PMID:8647386
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Gaspar NJ, et al. (1994) Translation initiation factor eIF-2. Cloning and expression of the human cDNA encoding the gamma-subunit. J Biol Chem 269(5):3415-22 PMID:8106381
    • SGD Paper
    • PubMed
  • Kinzy TG, et al. (1994) Multiple genes encode the translation elongation factor EF-1 gamma in Saccharomyces cerevisiae. Nucleic Acids Res 22(13):2703-7 PMID:8041634
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Hannig EM, et al. (1993) GCD11, a negative regulator of GCN4 expression, encodes the gamma subunit of eIF-2 in Saccharomyces cerevisiae. Mol Cell Biol 13(1):506-20 PMID:8417348
    • SGD Paper
    • DOI full text
    • PMC full text
    • PubMed
  • Wu S, et al. (1993) Cloning and characterization of complementary DNA encoding the eukaryotic initiation factor 2-associated 67-kDa protein (p67). J Biol Chem 268(15):10796-801 PMID:8496145
    • SGD Paper
    • PubMed
  • SGD
  • About
  • Blog
  • Help
  • Privacy Policy
  • Creative Commons License
© Stanford University, Stanford, CA 94305.
Back to Top