Gomes F, et al. (2025) Loss of G1-phase CDK-inhibition biases instability between genomic regions by unevenly reducing activity among replication origins. iScience 28(6):112757 PMID:40546943
Frattini C and Bermejo R (2019) Analysis of Cohesin Association to Newly Replicated DNA Through Nascent Strand Binding Assay (NSBA). Methods Mol Biol 2004:139-153 PMID:31147915
Ferrari E, et al. (2017) PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response. Mol Cell 67(2):266-281.e4 PMID:28648781
Colosio A, et al. (2016) Nucleolytic processing of aberrant replication intermediates by an Exo1-Dna2-Sae2 axis counteracts fork collapse-driven chromosome instability. Nucleic Acids Res 44(22):10676-10690 PMID:27672038
Gonzalez-Huici V, et al. (2014) DNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity. EMBO J 33(4):327-40 PMID:24473148
Alzu A, et al. (2012) Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes. Cell 151(4):835-846 PMID:23141540
Ray Chaudhuri A, et al. (2012) Topoisomerase I poisoning results in PARP-mediated replication fork reversal. Nat Struct Mol Biol 19(4):417-23 PMID:22388737
Gómez-González B, et al. (2011) Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles. EMBO J 30(15):3106-19 PMID:21701562
Fachinetti D, et al. (2010) Replication termination at eukaryotic chromosomes is mediated by Top2 and occurs at genomic loci containing pausing elements. Mol Cell 39(4):595-605 PMID:20797631
Bermejo R, et al. (2009) Genome-organizing factors Top2 and Hmo1 prevent chromosome fragility at sites of S phase transcription. Cell 138(5):870-84 PMID:19737516
Kerrest A, et al. (2009) SRS2 and SGS1 prevent chromosomal breaks and stabilize triplet repeats by restraining recombination. Nat Struct Mol Biol 16(2):159-67 PMID:19136956
Bermejo R, et al. (2007) Top1- and Top2-mediated topological transitions at replication forks ensure fork progression and stability and prevent DNA damage checkpoint activation. Genes Dev 21(15):1921-36 PMID:17671091