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Allele: tlc1-tm

Allele Name
tlc1-tm 1
SGD ID
SGD:S000313347
Affected Gene
TLC1
Allele Type
missense variant 1
Description
tlc1-tm mutant gives rise to telomere sequences that lack the GGG motif present in the wild-type repeat and, therefore, are expected to be impaired in the formation of G-quadruplexes 2

References

List of references used specifically to curate the information in Overview section.

  1. Rosas Bringas FR, et al. (2022) Rif2 protects Rap1-depleted telomeres from MRX-mediated degradation in <i>Saccharomyces cerevisiae</i>. Elife 11 PMID: 35044907
  2. Stinus S, et al. (2022) Investigating the role of G-quadruplexes at <i>Saccharomyces cerevisiae</i> telomeres. Microb Cell 9(6):126-132 PMID: 35795254

Resources

Mutant Strains

Phenotype Resources

Ontology

Yeast Phenotype Ontology

Interactions Resources