Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
9 entries for 6 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| MLO50 | competitive fitness: decreased | competitive growth fitness profiling using complete deletion alleles | null Allele: mlo50-Δ | S288C | Media: minimal medium Details: Relative fitness score: 0.965 | Breslow DK, et al. (2008) PMID:18622397 | |
| MLO50 | replicative lifespan: increased | systematic mutation set | null Allele: mlo50-Δ | S288C | Details: long-lived mutants, one standard deviation above the mean, were identified using an HTP sequencing-based yeast replicative lifespan screen (SEBYL), with pooled cells subject to four rounds of biotin-based sorting to enrich old vs young cells, followed by sequencing to ID mutants and abundance | Yu R, et al. (2021) PMID:33790287 | |
| MLO50 | resistance to chemicals: decreased | competitive growth fitness profiling of the non-essential deletion collection after 18 generations | null Allele: mlo50-Δ | S288C | 20 ug/ml cordycepin | Details: sensitivity increased two-fold or greater | Holbein S, et al. (2009) PMID:19324962 |
| MLO50 | resistance to chemicals: decreased | homozygous diploid, systematic mutation set | null Allele: mlo50-Δ | S288C | benzo[a]pyrene | O'Connor ST, et al. (2012) PMID:23403841 | |
| MLO50 | resistance to chemicals: decreased | homozygous diploid, systematic mutation set | null Allele: mlo50-Δ | S288C | 460 uM dieldrin | Gaytán BD, et al. (2013) PMID:23358190 | |
| MLO50 | resistance to chemicals: increased | homozygous diploid, systematic mutation set | null Allele: mlo50-Δ | S288C | 640 uM toxaphene | Gaytán BD, et al. (2013) PMID:24260565 | |
| MLO50 | sporulation: normal | homozygous diploid, systematic mutation set Visual inspection by light microscopy | null Allele: mlo50-Δ | SK1 | Rabitsch KP, et al. (2001) PMID:11470404 | ||
| MLO50 | viable | systematic mutation set | null Allele: mlo50-Δ | S288C | Giaever G, et al. (2002) PMID:12140549 | ||
| MLO50 | viable | homozygous diploid, systematic mutation set | null Allele: mlo50-Δ | SK1 | Rabitsch KP, et al. (2001) PMID:11470404 |
This diagram displays up to the top 30 positive interactions (green), negative interactions (orange), and phenotypes (blue) that are shared between the given allele (black) and other alleles (purple). The shared interactions or phenotypes can be visualized separately using the radio button at the bottom of the graph.
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