Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
2 entries for 2 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
---|---|---|---|---|---|---|---|
RAD5 | mitotic recombination: decreased | classical genetics | reduction of function Allele: rad5-D681A,E682A mutations confer deficiency in helicase function | S288C | 10 M 4-nitroquinoline N-oxide | Details: 2.7-fold induction of 4NQO-associated recombination compared to 9-fold for wild-type | Fasullo MT and Sun M (2017) PMID:28596989 |
RAD5 | resistance to chemicals: decreased | classical genetics | reduction of function Allele: rad5-D681A,E682A | S288C | 10 M 4-nitroquinoline N-oxide | Fasullo MT and Sun M (2017) PMID:28596989 |
List of references used specifically to curate the information in Overview section.
Addgene Plasmids | DNASU Plasmids | PlasmID | Thermo Scientific | YGRC
dHITS | FitDB | HIPHOP Chemogenomics | HIP HOP Profiles | MetaboGeneCard | PROPHECY | SCMD | ScreenTroll | TheCellVision | Yeast Phenome
BioGRID | CYC2008 | DIP | GeneMANIA | IMP | InterologFinder | ModelArchive | TheCellMap