Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
10 entries for 8 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
---|---|---|---|---|---|---|---|
MSS4 | actin cytoskeleton morphology: abnormal | classical genetics | conditional Allele: mss4-2 | JK9-3d | Temperature: elevated temperature, 37 °C Details: unable to form actin cables; actin cortical patches randomly distributed | Desrivières S, et al. (1998) PMID:9624178 | |
MSS4 | chemical compound accumulation: decreased | classical genetics | conditional Allele: mss4-2 | JK9-3d | 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate | Temperature: elevated temperature, 37 °C Details: 10% of wild-type levels | Desrivières S, et al. (1998) PMID:9624178 |
MSS4 | endocytosis: decreased Reporter: a-factor pheromone | classical genetics | conditional Allele: mss4-2 | JK9-3d | Temperature: elevated temperature, 37 °C Details: defective receptor-mediated endocytosis | Desrivières S, et al. (2002) PMID:12079494 | |
MSS4 | endocytosis: decreased Reporter: lucifer yellow | classical genetics | conditional Allele: mss4-2 | JK9-3d | Temperature: elevated temperature, 37 °C Details: defective fluid-phase endocytosis | Desrivières S, et al. (2002) PMID:12079494 | |
MSS4 | heat sensitivity: increased | classical genetics | conditional Allele: mss4-2 | JK9-3d | Temperature: elevated temperature, 37 °C | Desrivières S, et al. (1998) PMID:9624178 | |
MSS4 | meiosis: decreased | homozygous diploid | conditional Allele: mss4-2 | SK1 | Temperature: elevated temperature, 34.5 °C | Rudge SA, et al. (2004) PMID:14528019 | |
MSS4 | protein/peptide distribution: abnormal Reporter: HA-Slm1p | classical genetics | conditional Allele: mss4-2 | JK9-3d | Temperature: elevated temperature, 38 °C Details: redistribution from the plasma membrane to the cytoplasm | Fadri M, et al. (2005) PMID:15689497 | |
MSS4 | protein/peptide distribution: abnormal Reporter: HA-Slm1p | classical genetics | conditional Allele: mss4-2 | JK9-3d | Temperature: permissive temperature, 25 °C Details: redistribution from the plasma membrane to the cytoplasm | Fadri M, et al. (2005) PMID:15689497 | |
MSS4 | sporulation: decreased | homozygous diploid | conditional Allele: mss4-2 | SK1 | Temperature: elevated temperature, 34.5 °C | Rudge SA, et al. (2004) PMID:14528019 | |
MSS4 | viability: decreased | classical genetics | conditional Allele: mss4-2 | JK9-3d | Temperature: elevated temperature, 37 °C Details: cells start to die after 2 hours resulting in the accumulation of ghosts | Desrivières S, et al. (1998) PMID:9624178 |
This diagram displays up to the top 30 positive interactions (green), negative interactions (orange), and phenotypes (blue) that are shared between the given allele (black) and other alleles (purple). The shared interactions or phenotypes can be visualized separately using the radio button at the bottom of the graph.
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