Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
43 entries for 25 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| PET111 | autophagy: decreased | classical genetics | null Allele: pet111-Δ | W303 | Media: amino acid starvation with acetate (non-fermentable) carbon source Details: autophagic flux measured by the ratio of free GFP (resulting from autophagic degradation of Atg8p-GFP fusion) to total GFP | Graef M and Nunnari J (2011) PMID:21468027 | |
| PET111 | cell size: decreased | systematic mutation set analysis of cell size for mutants in the systematic deletion collection | null Allele: pet111-Δ | S288C | Details: mutant is among the smallest 5% of haploid deletion strains | Jorgensen P, et al. (2002) PMID:12089449 | |
| PET111 | chemical compound accumulation: abnormal | systematic mutation set | null Allele: pet111-Δ | S288C | alpha-amino acid | Details: Significantly altered free amino acid profile (X^2- test p < 0.01), showing 1 simultaneous amino acid change (Z-test, adjusted p < 0.01) | Mülleder M, et al. (2016) PMID:27693354 |
| PET111 | chemical compound accumulation: decreased | homozygous diploid, systematic mutation set glycogen accumulation in diploid mutant strains grown in microtiter plates | null Allele: pet111-Δ | S288C | glycogen | Wilson WA, et al. (2002) PMID:12096123 | |
| PET111 | chemical compound accumulation: decreased | systematic mutation set | null Allele: pet111-Δ | S288C | proton | Media: external pH 5.0 | Orij R, et al. (2012) PMID:23021432 |
| PET111 | chemical compound accumulation: decreased | systematic mutation set | null Allele: pet111-Δ | S288C | proton | Media: external pH 7.5 | Orij R, et al. (2012) PMID:23021432 |
| PET111 | chemical compound accumulation: decreased | systematic mutation set | null Allele: pet111-Δ | S288C | asparagine | Mülleder M, et al. (2016) PMID:27693354 | |
| PET111 | chemical compound accumulation: increased | systematic mutation set | null Allele: pet111-Δ | S288C | proton | Media: external pH 3.0 | Orij R, et al. (2012) PMID:23021432 |
| PET111 | chromosome/plasmid maintenance: decreased | heterozygous diploid, systematic mutation set | null Allele: pet111-Δ | S288C | Assay: diploid bimater (BiM) assay Details: haploinsufficiency results in chromosome instability (CIN); scored >= 2 standard deviations above the mean | Choy JS, et al. (2013) PMID:23825022 | |
| PET111 | chronological lifespan: decreased | systematic mutation set | null Allele: pet111-Δ | S288C | Marek A and Korona R (2013) PMID:24151994 |
An interaction is defined as an experimentally observed physical or genetic interaction between two genes. There may be more than one row listed for the same interactor if the interaction between it and the given gene was observed in separate studies. All interactions listed in SGD are curated by BioGRID.
Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details about experiment type and any other genes involved in the interaction.
| Evidence ID | Analyze ID | Interactor | Interactor Systematic Name | Interactor | Interactor Systematic Name | Allele | Assay | Annotation | Action | Phenotype | SGA score | P-value | Source | Reference | Note |
|---|
This diagram displays up to the top 30 positive interactions (green), negative interactions (orange), and phenotypes (blue) that are shared between the given allele (black) and other alleles (purple). The shared interactions or phenotypes can be visualized separately using the radio button at the bottom of the graph.
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