Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
14 entries for 11 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
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SFB3 | acid pH resistance: decreased | classical genetics | null Allele: sfb3-Δ | Other | hydrogen chloride | Media: low pH, pH 3.8 | Roberg KJ, et al. (1999) PMID:10330397 |
SFB3 | cellular morphology: abnormal | classical genetics | null Allele: sfb3-Δ | Other | Details: at pH 3.8, 10% of cells form multibudded cells | Roberg KJ, et al. (1999) PMID:10330397 | |
SFB3 | heat sensitivity: increased | heterozygous diploid, systematic mutation set pooled screening for fitness defects at 37 deg C relative to 30 deg C | null Allele: sfb3-Δ | S288C | Temperature: elevated temperature, 37 °C | Sinha H, et al. (2008) PMID:18780730 | |
SFB3 | prion formation: decreased Reporter: [GAR+] prion | classical genetics | null Allele: sfb3-Δ | W303 | Brown JC and Lindquist S (2009) PMID:19797769 | ||
SFB3 | protein transport: abnormal Reporter: Pma1p | classical genetics | null Allele: sfb3-Δ | Other | Roberg KJ, et al. (1999) PMID:10330397 | ||
SFB3 | protein/peptide accumulation: increased Reporter: Gas1p | classical genetics | null Allele: sfb3-Δ | Other | Peng R, et al. (2000) PMID:10753972 | ||
SFB3 | protein/peptide accumulation: increased Reporter: Pma1p | classical genetics | null Allele: sfb3-Δ | Other | Roberg KJ, et al. (1999) PMID:10330397 | ||
SFB3 | protein/peptide distribution: abnormal Reporter: Pma1p | classical genetics | null Allele: sfb3-Δ | Other | Details: accumulates in the ER and not at the cell surface | Roberg KJ, et al. (1999) PMID:10330397 | |
SFB3 | protein/peptide modification: decreased rate Reporter: Gas1p decreased maturation from precursor to Golgi-modified mature form | classical genetics | null Allele: sfb3-Δ | S288C | D'Arcangelo JG, et al. (2015) PMID:25936552 | ||
SFB3 | resistance to chemicals: decreased | homozygous diploid, systematic mutation set | null Allele: sfb3-Δ | S288C | 5 ug/ml phleomycin D1 | Krol K, et al. (2015) PMID:25756177 |
An interaction is defined as an experimentally observed physical or genetic interaction between two genes. There may be more than one row listed for the same interactor if the interaction between it and the given gene was observed in separate studies. All interactions listed in SGD are curated by BioGRID.
Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details about experiment type and any other genes involved in the interaction.
Evidence ID | Analyze ID | Interactor | Interactor Systematic Name | Interactor | Interactor Systematic Name | Allele | Assay | Annotation | Action | Phenotype | SGA score | P-value | Source | Reference | Note |
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This diagram displays up to the top 30 positive interactions (green), negative interactions (orange), and phenotypes (blue) that are shared between the given allele (black) and other alleles (purple). The shared interactions or phenotypes can be visualized separately using the radio button at the bottom of the graph.
Addgene Plasmids | DNASU Plasmids | PlasmID | Thermo Scientific | YGRC
dHITS | FitDB | HIPHOP Chemogenomics | HIP HOP Profiles | MetaboGeneCard | PROPHECY | SCMD | ScreenTroll | TheCellVision | Yeast Phenome
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