Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
28 entries for 17 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| DLT1 | acquired thermotolerance: decreased | systematic mutation set | null Allele: dlt1-Δ | S288C | Treatment: heat shock, 50 °C Details: pretreatment at 37 deg C for 1 hour, followed by heat shock for 0, 3, 6, 9, 12, or 15 min; innate thermotolerance is normal | Gibney PA, et al. (2013) PMID:24167267 | |
| DLT1 | chemical compound accumulation: increased | homozygous diploid, systematic mutation set glycogen accumulation in diploid mutant strains grown in microtiter plates | null Allele: dlt1-Δ | S288C | glycogen | Wilson WA, et al. (2002) PMID:12096123 | |
| DLT1 | chronological lifespan: increased | systematic mutation set | null Allele: dlt1-Δ | S288C | Campos SE, et al. (2018) PMID:29575540 | ||
| DLT1 | cold sensitivity: increased | systematic mutation set | null Allele: dlt1-Δ | S288C | Temperature: reduced temperature, 15 °C Details: growth is reduced by 50% of more relative to wt after exposure to reduced temperature for 20 hours at atmospheric pressure | Abe F and Minegishi H (2008) PMID:18245339 | |
| DLT1 | competitive fitness: decreased | competitive growth fitness profiling using complete deletion alleles | null Allele: dlt1-Δ | S288C | Media: minimal medium Details: Relative fitness score: 0.963 | Breslow DK, et al. (2008) PMID:18622397 | |
| DLT1 | competitive fitness: decreased | systematic mutation set | null Allele: dlt1-Δ | S288C | Media: glycerol medium, YPG | Qian W, et al. (2012) PMID:23103169 | |
| DLT1 | competitive fitness: decreased | systematic mutation set | null Allele: dlt1-Δ | S288C | Media: synthetic complete medium, SC | Qian W, et al. (2012) PMID:23103169 | |
| DLT1 | competitive fitness: decreased | systematic mutation set | null Allele: dlt1-Δ | S288C | Media: synthetic oak exudate medium, OAK | Qian W, et al. (2012) PMID:23103169 | |
| DLT1 | endocytosis: decreased | systematic mutation set | null Allele: dlt1-Δ | S288C | Details: defective internalization of a chimeric Snc1p reporter, GFP-Snc1-Suc2 | Burston HE, et al. (2009) PMID:19506040 | |
| DLT1 | hydrostatic pressure resistance: decreased | systematic mutation set | null Allele: dlt1-Δ | S288C | Treatment: high pressure, 25 MPa Details: growth is reduced by 50% of more relative to wt after exposure to high pressure in a hydrostatic chamber | Abe F and Minegishi H (2008) PMID:18245339 |
An interaction is defined as an experimentally observed physical or genetic interaction between two genes. There may be more than one row listed for the same interactor if the interaction between it and the given gene was observed in separate studies. All interactions listed in SGD are curated by BioGRID.
Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details about experiment type and any other genes involved in the interaction.
| Evidence ID | Analyze ID | Interactor | Interactor Systematic Name | Interactor | Interactor Systematic Name | Allele | Assay | Annotation | Action | Phenotype | SGA score | P-value | Source | Reference | Note |
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This diagram displays up to the top 30 positive interactions (green), negative interactions (orange), and phenotypes (blue) that are shared between the given allele (black) and other alleles (purple). The shared interactions or phenotypes can be visualized separately using the radio button at the bottom of the graph.
Addgene Plasmids | DNASU Plasmids | PlasmID | Thermo Scientific | YGRC
dHITS | FitDB | HIPHOP Chemogenomics | HIP HOP Profiles | MetaboGeneCard | PROPHECY | SCMD | ScreenTroll | TheCellVision | Yeast Phenome
BioGRID | CYC2008 | GeneMANIA | IMP | InterologFinder | ModelArchive | TheCellMap