Primary Literature
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- Yokoyama M, et al. (2023) Spt4 promotes cellular senescence by activating non-coding RNA transcription in ribosomal RNA gene clusters. Cell Rep 42(1):111944 PMID: 36640349
- Chen F, et al. (2022) The Paf1 complex is required for RNA polymerase II removal in response to DNA damage. Proc Natl Acad Sci U S A 119(40):e2207332119 PMID: 36161924
- Uzun Ü, et al. (2021) Spt4 facilitates the movement of RNA polymerase II through the\xa0+2 nucleosomal barrier. Cell Rep 36(13):109755 PMID: 34592154
- Ólafsson G and Thorpe PH (2020) Polo kinase recruitment via the constitutive centromere-associated network at the kinetochore elevates centromeric RNA. PLoS Genet 16(8):e1008990 PMID: 32810142
- Silva A, et al. (2017) Regulation of transcription elongation in response to osmostress. PLoS Genet 13(11):e1007090 PMID: 29155810
- Blythe AJ, et al. (2016) The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein. Protein Sci 25(9):1710-21 PMID: 27376968
- Crickard JB, et al. (2016) Biochemical Analysis of Yeast Suppressor of Ty 4/5 (Spt4/5) Reveals the Importance of Nucleic Acid Interactions in the Prevention of RNA Polymerase II Arrest. J Biol Chem 291(19):9853-70 PMID: 26945063
- Blythe A, et al. (2014) Ubiquitin fusion constructs allow the expression and purification of multi-KOW domain complexes of the Saccharomyces cerevisiae transcription elongation factor Spt4/5. Protein Expr Purif 100:54-60 PMID: 24859675
- Mosley AL, et al. (2013) Quantitative proteomics demonstrates that the RNA polymerase II subunits Rpb4 and Rpb7 dissociate during transcriptional elongation. Mol Cell Proteomics 12(6):1530-8 PMID: 23418395
- Anderson SJ, et al. (2011) The transcription elongation factor Spt5 influences transcription by RNA polymerase I positively and negatively. J Biol Chem 286(21):18816-24 PMID: 21467039
- Martinez-Rucobo FW, et al. (2011) Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity. EMBO J 30(7):1302-10 PMID: 21386817
- Viktorovskaya OV, et al. (2011) Yeast transcription elongation factor Spt5 associates with RNA polymerase I and RNA polymerase II directly. J Biol Chem 286(21):18825-33 PMID: 21467036
- Zhou K, et al. (2009) Control of transcriptional elongation and cotranscriptional histone modification by the yeast BUR kinase substrate Spt5. Proc Natl Acad Sci U S A 106(17):6956-61 PMID: 19365074
- Guo M, et al. (2008) Core structure of the yeast spt4-spt5 complex: a conserved module for regulation of transcription elongation. Structure 16(11):1649-58 PMID: 19000817
- Schneider DA, et al. (2006) RNA polymerase II elongation factors Spt4p and Spt5p play roles in transcription elongation by RNA polymerase I and rRNA processing. Proc Natl Acad Sci U S A 103(34):12707-12 PMID: 16908835
- Lindstrom DL, et al. (2003) Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins. Mol Cell Biol 23(4):1368-78 PMID: 12556496
- Rondón AG, et al. (2003) Molecular evidence for a positive role of Spt4 in transcription elongation. EMBO J 22(3):612-20 PMID: 12554661
- Hartzog GA, et al. (1998) Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae. Genes Dev 12(3):357-69 PMID: 9450930